sheng lab broad institute sheng lab broad institute

Our researchers use their expertise in creating, adapting, and applying a variety of technologies to enable science here and beyond. Key scientific datasets and computational tools developed by our scientists and their collaborators. At Genentech he built and led a world-class neuroscience department and research program focused on elucidating pathologic mechanisms and developing new treatments for neurodegenerative diseases and pain, and illuminating pathways that are of basic scientific interest as well as therapeutic relevance. From 2008 to 2019, Sheng was vice-president of neuroscience at Genentech, a leading biotech company, where he led research and drug discovery efforts for major diseases of the nervous system. See Adata Technology 's products and customers Thousands of companies like you use Panjiva to research suppliers and competitors. Receive regular updates on Broad news, research and community. The Gerstner Center is developing next-generation diagnostic technology for cancer detection and tracking disease progression. (+1) 617-324-0305 Research Scientist I - Therapeutics Group - Sheng Lab. Dr. Pan has more than 15 years of experience investigating the function, molecular genetics and pharmacology of ion channels. 2. Zizhang Sheng is an associated research scientist in the Honig-Shapiro labs. Morgan Sheng is a core institute member of the Broad Institute of MIT and Harvard, where he serves as co-director of the Broads Stanley Center for Psychiatric Research. Dr. Sheng lab haspublisheda number of important studies focused on axonal transport of mitochondria and endolysosomes in healthy and diseased neurons. 46-1303 Cambridge, MA 02139 . In 2021, our sustainability efforts sent more than 80 percent of waste from the Genomics Platform to either a recycling facility or to an incineration plant that generates electricity. View all Broad Institute jobs in Cambridge, MA - Cambridge jobs; Salary Search: Laboratory Operations Coordinator - Stanley Center salaries in Cambridge, MA; See popular questions & answers about Broad Institute; new. He joined NINDS as an investigator in 1997 and is now a tenured senior investigator and Chief of Synaptic Functions Section at National Institute of Neurological Disorders and Stroke (NINDS), NIH. The Gerstner Center is developing next-generation diagnostic technology for cancer detection and tracking disease progression. gu_hongcang@hotmail.com. The address is No. His work has uncovered the form and complexity of protein complexes in the postsynaptic membrane that regulate the remarkable plasticity of neuronal connections. Postdoctoral Associate - Sheng Lab Broad Institute of MIT and Harvard Cambridge, MA 1 month ago Be among the first 25 applicants jleonard@caltech.edu. I am excited to return to academia and establish a research lab at the Broad, said Sheng. Developing a resistant cultivar and inducing plant defenses by elicitor application are currently two of the best options to control this disease. The Broad Institute of MIT & Harvard is looking for outstanding postdoctoral scholars to join the laboratory of Morgan Sheng, Co-Director of theStanley Center for Psychiatric Research, The mission of the Stanley Center is to improve the lives of patients suffering from serious mental illnesses, through groundbreaking basic and translational research. Dr. Sheng Lin-Gibson is the Chief of the Biosystems and Biomaterials Division (BBD) at the National Institute of Standards and Technology (NIST). Please contact Prof. Sheng-Yang He (shengyang.he@duke.edu; hes@msu.edu). My research will involve a combination of organic synthesis, microbiology, molecular biology, enzymology, and potential optimization of . https://doi.org/10.1038/s41593-022-01251-x. Currently, the Sheng lab focuses on three areas of research: Immune response to infection and vaccination: We develop computational methods to study immune responses of humans and animal models. Yeh FL, Wang Y, Tom I, Gonzalez LC, Sheng M. Neuron 2016 Jul 20;91(2):328-40. Broad brings people together to advance the understanding and treatment of disease. Institute Member, Broad Institute of MIT and Harvard Office: 46-3143A / Phone: (617) 715-4898 . Lei received his PhD in Neuroscience under the doctoral program of "Molecular Physiology of the Brain" Nikita completed his Cognitive Science Bachelor's degree from McGill university in the spring of 2019 focusing in the fields of Neuroscience and Philosophy. By creating this job alert, you agree to the LinkedIn User Agreement and Privacy Policy. Professor, Department of Otolaryngology - Head and Neck Surgery; . Dr. Sheng was elected to AAAS Fellow in 2016 and ASCB fellow in 2017 for his contributions to the field of axonal transport of mitochondria and endolysosomes in maintenance of neuronal homeostasis and synaptic function in health and diseases. As Co-Director of the Stanley Center for Psychiatric Research at the Broad Institute, Sheng will help to shape the centers scientific vision and direction, and oversee the centers efforts to develop therapeutics for schizophrenia and other serious mental illnesses. He continues to collaborate with the lab as PhD student in the Stanford Genetics program. The observed reaction rate is . In February of 2020 he joined the Stanley Nathaniel Goble graduated from the University of Southern California in 2021 with a major in neuroscience and minor in philosophy. Picower research on the disorder includes creating stem cell lines and lab tissues, providing new insights into the molecular and cell biology of the disorder, and studying systems level interventions. About. Cambridge, MA 02142 (Kendall Square area) Full-time. Work with other Broad computational biologists, including those in the Levin group to learn, discuss, and integrate the most appropriate solution for an experiment or project. Posted on July 4, 2022 by . Shawn.Sheng@nrel.gov 303-384-7106 . Senior investigator, Chief of Synaptic Functions Section, NINDS, NIH. 415 Main St. Job functions Engineering, Information Technology, Operations. 4.2 Laboratory diagnosis . Fralin Biomedical Research Institute faculty conduct research in wet and dry labs in our 280,000-square-foot facilities . Check out this video for a look into our community! Salaries below this are outliers. He is also a professor of neuroscience in MITs Department of Brain and Cognitive Sciences, and an affiliate of both The Picower Institute for Learning and Memory and the McGovern Institute for Brain Research. The P4 lab is located in a new developing zone about one hour car ride from the current institute location in central Wuhan city. Fei was a Schmidt Fellow at the Broad Institute from 2017-2020. 2018 Dec 19;100(6):1322-1336.e7. All Broad employees, regardless of work location, must be fully vaccinated for COVID-19 by Tuesday, October 12, 2021. His Ph.D. thesis was completed at Harvard Medical School in the lab of Michael Greenberg. Important new look into the Alzheimer's brain from a collaboration including Morgan Sheng, a Picower Institute affiliate professor based at . The trainees in core faculty labs are typically engaged in one or more of the Broad programs, and often benefit from and collaborate with the Broad platforms. Sheng received a B.A. Cambridge, MA 02139-4307 |(617) 253-5748, For Emergencies|Accessibility|Adapting to COVID, A physician and a scientist, Morgan Sheng. Lab Affiliation: Postdoctoral Associate Mar 2016 - Dec 2016. 2 Zhejiang Sheng Ting Biotechnology Company, Hangzhou, Zhejiang, P. R. China. 908: He was first trained as a molecular biologist in the University of Hong Kong Sean Moran is a neuropharmacologist with a strong passion for translational neuroscience research who earned his PhD from Vanderbilt University under the mentorship of P. Jeffrey Conn. During his Lei is an interdisciplinary scientist with skills in neuroscience, machine learning, and software development. At MIT from 2001 to 2008, he served as professor in the Department of Brain and Cognitive Sciences and the Department of Biology, was a member of the Picower Institute for Learning and Memory, and was a Howard Hughes Medical Institute investigator. 69, Lide St. Zhonghe Dist., New Taipei City, TW. Sheng laboratory focuses on mechanisms regulating axonal transport that is essential for the maintenance of synaptic function and axonal homeostasis. Structural Insights of Non-canonical U-U Pair and Hoogsteen Interaction Probed with Se Atom. msheng@mit.edu. Much of the oral arguments centered on legal standing, which is the right of a party to bring a lawsuit to court.In the first case, Biden v. Nebraska, several justices questioned whether Missouri one of six states suing had the right to bring a case on behalf of Mohela, an independent state-created student loan servicer. In 2020 she graduated from Rutgers University with her MS in Biomedical Science with a concentration in Neuroscience. The MIT Department of Biology ("Course VII") is a center for research and teaching in the life sciences. Click the link in the email we sent to to verify your email address and activate your job alert. Post-cardiac arrest syndrome: epidemiology, pathophysiology, treatment, and prognostication. Massachusetts Institute of Technology. Researchers anywhere can explore more than 6,000 drugs in the hub and search for possible new uses for them to jump-start new drug discovery. Lab studies the genetics underlying neural development to identify new diagnostic and therapeutic approaches for a broad range of disorders that compromise brain and organ system development. Washington, DC; Chicago, IL; New York, NY; San Francisco, CA; Dallas, TX; Search. Copyright 2008-2023, Glassdoor, Inc. "Glassdoor" and logo are registered trademarks of Glassdoor, Inc, The Broad Institute of MIT & Harvard is looking for outstanding postdoctoral scholars to join the laboratory of Morgan Sheng, Co-Director of the. In collaboration with labs at ADARC, we sequence viral antigen-specific B cell receptors (BCRs) to identify immune signatures of infections including . Published in NANO Letters, the study was led by Zhi Sheng and Deborah . Following postdoctoral research in the lab of Lily Jan at the University of . Postdoctoral Associate - Sheng Lab in The Broad Institute, Inc. Cambridge, MA. By the end of 2022, Broads COVID-19 testing lab had processed more than 37 million tests. , United States. I am currently an Associate Computational Biologist II in the Morgan Sheng lab at the Broad Institute of MIT and Harvard. The Stanley Center has gained unprecedented insight into the genetic basis of psychiatric illness (schizophrenia, bipolar disorder, autism). The long-term goal of the laboratory is to decipher mechanisms (1) boosting axonal and synaptic energy metabolism and (2) enhancing autophagy-lysosomal function for efficient clearance of dysfunctional organelles and aggregated proteins that are associated with major neurodegenerative diseases. Background and aimsAs a result of increasing numbers of studies most recently, mitophagy plays a vital function in the genesis of cancer. Through Broad's Scientists in the Classroom program, Broad researchers visit every 8th grade classroom in Cambridge each year to talk about genetics and evolution. Biological products exc.diagnostic Umbilical cord blood stem cells and collection, storage, should be the technical services and research and development) Sheng Lin-Gibson is the chief of the Biosystems and Biomaterials Division at the National Institute of Standards and Technology (NIST). Morgan Sheng is a core institute member of the Broad Institute of MIT and Harvard, where he serves as co-director of the Broads Stanley Center for Psychiatric Research. . I am looking forward to joining this community of innovative researchers and applying my expertise to discover novel therapies and improve the lives of people with mental illness.. Neumar RW, Nolan JP, Adrie C, et al. A multimodal molecular cell-type atlas of the MOp. Copyright 2008-2023, Glassdoor, Inc. "Glassdoor" and logo are registered trademarks of Glassdoor, Inc, Computational Associate II, Stanley Center for Psychiatric Research, Title: Computational Associate II, Stanley Center for Psychiatric Research. Yun-Sheng received his master's degrees in materials science and engineering from . the broad institute of mit & harvard is looking for outstanding postdoctoral scholars to join the laboratory of morgan sheng, co-director of the stanley center for psychiatric research, the mission. The Drug Repurposing Hub is one of the most comprehensive and up-to-date biologically annotated collections of FDA-approved compounds in the world. Nature neuroscience 12 (4), 428-437, 2009. . EEO is The Law - click here for more information, Equal Opportunity Employer Minorities/Women/Protected Veterans/Disabled. Mailing address: California Institute of Technology. Job Description The Broad Institute of MIT & Harvard is looking for outstanding postdoctoral scholars to join the laboratory of Morgan Sheng, Co-Director of the Stanley Center for Psychiatric Research, The mission of the Stanley Center is to improve the lives of patients suffering from serious mental illnesses, through groundbreaking basic and translational research. Discover remarkable stories of scientific progress, and explore the intersections of science, medicine, and society. . In this paper, the effects of ultrasound frequency (17-25 kHz), power . The McGovern Institute is an integral part of MIT with a board that includes representatives appointed by the McGovern family and by MIT. In March of 2020, Broad Institute converted a clinical genetics processing lab into a large-scale COVID-19 testing facility in less than two weeks. This person will apply existing computational methods and interpret results within a biological context. Avoid inappropriate use of antibacterial drugs, especially the combined use of broad-spectrum antibacterial drugs. Here, we report a single-molecule approach capable of . Is this useful? Laboratory Technician 1,190 job openings. This position in the Stanley Center for Psychiatric Research involves bioinformatics analysis in areas such as transcriptomics, neurophysiology, and behavior. Long-Sheng Chang, PhD. She leads the ICE-T (ion channel electrophysiology and technology) effort enabled by Broadnext10 initiative to utilize state-of-art technologies for studying ion channels and electrogenic transporters, and to find novel ways to modulate these highly specialized membrane proteins. Ma Huang (Ephedrae Herba) 9 g, Zhi Gan Cao (Glycyrrhizae Radix) 6 g, Xing Ren (Armeniacae Semen) 9 g, Sheng Shi Gao (Gypsum fibrosum . He has served as a mentor for 8 graduate students (NIH joint PhD Programs), 6 HHMI-NIH research scholars, and 20 postdoctoral fellows. Hu Zeng, Jiahao Huang, Haowen Zhou, William J. Meilandt, Borislav Dejanovic, Yiming Zhou, Christopher J. Bohlen, Seung-Hye Lee, Jingyi Ren, Albert Liu, Zefang Tang, Hao Sheng, Jia Liu, Morgan Sheng & Xiao Wang, Nat Neurosci (2023). The Stanley Center has gained unprecedented insight into the genetic basis of psychiatric illness (schizophrenia, bipolar disorder, autism). (+1) 617-452-2588. We seek to understand how lipid macromolecules are generated, stored, and metabolized, and how lipid processes function in membrane biology and cell physiology. Website. Cambridge, MA 02139 Dr. Sheng received his Ph.D. in Biochemistry from the University of Pennsylvania in 1993. Morgan Sheng is a core institute member of the Broad Institute of MIT and Harvard, where he serves as co-director of the Broads Stanley Center for Psychiatric Research. Average $24.55 per hour. Research Areas . The Stanley Center has gained unprecedented insight into the genetic basis of psychiatric illness (schizophrenia, bipolar disorder, autism). Then she was a postdoctoral research scientist in the laboratory of Richard Axel at Columbia University. In November 2022, Broads Genomics Platform sequenced its 500,000th whole human genome, a mere four years after sequencing its 100,000th. 32. Professor of Biology; Core Member, Broad Institute; Investigator, Howard Hughes Medical Institute. Yun-Sheng Chen is an assistant professor at the University of Illinois, Urbana-Champaign. LinkedIn profile About the Lab. The Farese/Walther lab studies lipid and energy metabolism in cells. Dr. Fei Chen is currently a Core Faculty member at the Broad Institute, and assistant professor at Harvard Stem Cell and Regenerative Biology. The Drug Repurposing Hub is one of the most comprehensive and up-to-date biologically annotated collections of FDA-approved compounds in the world. Researchers in the Sheng . From 2008 to 2019, Sheng was vice-president of neuroscience at Genentech, a leading biotech company, where he led research and drug discovery efforts for major diseases of the nervous system. We are seeking a motivated Computational Associate II (CA) to join the Sheng Lab at the Broad Institute of MIT and Harvard. AY Hung, M Sheng. Should have a demonstrated proficiency in R and/or Python, or related languages, Experience with and solid understanding of statistical analysis is required, Familiarity with next-generation sequence data analysis tools and packages, particularly those for bulk and single cell/nucleus RNA-seq, Understanding of molecular biology and next generation sequencing is highly preferred, Familiarity with working on a computing cluster/server (important skills: Unix/Linux, shell scripting). Published in NANO Letters, the study was led by Zhi Sheng and Deborah . Email. 46-5285. . Nucleic Acids Research, 2013, 41, 10476-10487. Broad Institute of MIT and Harvard - Cited by 75,072 - neuroscience . To combat the COVID-19 pandemic, nonpharmaceutical interventions (NPI) were implemented worldwide, which impacted a broad spectrum of acute respiratory infections (ARI).Etiologically diagnostic data from 142 559 cases with ARIs, who were tested for eight . Working with Addgene, Broad Institute has shared CRISPR genome-editing reagents with researchers at more than 3,200 institutions in 76 countries. By the end of 2022, Broads COVID-19 testing lab had processed more than 37 million tests. Fralin Biomedical Research Institute faculty conduct research in wet and dry labs in our 280,000-square-foot facilities . Broad Genomics Platform sequences a whole human genome every four minutes. Lab website. We join with institutions and scientists the world over to address foundational challenges in science and health. Sheng spent the past 10 years at Genentech, a preeminent biotech company, as Vice-President of Neuroscience. Isotianil is a monocarboxylic acid amide that has been used as a fungicide to control rice blast and could potentially induce systemic . Sheng is an elected Fellow of the Royal Society (UK), the Academy of Medical Sciences (UK), and the AAAS. Oana Ursu Status: Postdoc, Aviv Regev lab, Broad Institute Lab Affiliation: PhD, Genetics Dept., Co-advised by Mike Snyder Sept 2013 - Mar 2018 (HHMI International Fellow) Research focus: 3D genome organization, enhancer-gene linking, regulatory . $160,000.00. His work has uncovered the form and complexity of protein complexes in the postsynaptic membrane that regulate the remarkable plasticity of neuronal connections. You can unsubscribe from these emails at any time. Explore the connection between art and science and how we bring together artists and Broad scientists through our artist-in-residence program, gallery exhibitions, and ongoing public conversations. This candidate will collaborate with biologists and geneticists to perform various analysis including transcriptomics and proteomics analysis, pathway analysis and biological interpretations. The Eli and Edythe L. Broad Institute of MIT and Harvard (IPA: / b r o d /, pronunciation respelling: BROHD), often referred to as the Broad Institute, is a biomedical and genomic research center located in Cambridge, Massachusetts, United States.The institute is independently governed and supported as a 501(c)(3) nonprofit research organization under the name Broad Institute Inc., and it . The Merkin Institute is supporting early-stage ideas aimed at advancing powerful technological approaches for improving how we understand and treat disease. We are a team of scientists studying the genetic basis and molecular mechanisms underlying schizophrenia and other brain disorders. The location will be the new campus for the entire institute in the near future (a lot of construction is going on right now). Learn about breakthroughs from Broad scientists. This center is developing new paradigms and technologies to scale the discovery of biological mechanisms of common, complex diseases, by facilitating close collaborations between the Broad Institute and the Danish research community. Discover remarkable stories of scientific progress, and explore the intersections of science, medicine, and society. 910: 2001: PDZ domains: structural modules for protein complex assembly. A catalog of scientific papers published by our members and staff scientists. Sheng Ding, PhD Senior Investigator, Gladstone Institutes . He has served on the editorial boards of Neuron, Journal of Neuroscience, and Current Opinions in Neurobiology. Following postdoctoral research in the lab of Lily Jan at the University of California, San Francisco, Sheng served as a faculty member in the Department of Neurobiology at Massachusetts General Hospital and Harvard Medical School (1994-2001) before joining MIT (2001-2008). Nathaniel earned his MA in psychology from Boston University in 2022 William Ned Martenis is a therapeutics group research associate affiliated with the Pan and Sheng labs, where he primarily develops, troubleshoots, and runs high-throughput assays designed to better Kate graduated from American University in 2016 with a BA in Psychology. He will also return to MIT, after a decade in industry, as a professor of neuroscience in the Department of Brain and Cognitive Sciences, where he will be an affiliate of both the McGovern Institute for Brain Research and the Picower Institute for Learning and Memory. This study aimed to uncover and analyze the mitophagy-related diagnostic biomarkers in HCC using . Distinguished Investigator and Professor at Gladstone Institute of Cardiovascular Disease, and Department of Pharmaceutical Chemistry, University of California San Francisco. We are seeking a motivated Computational Associate II (CA) to join the Sheng Lab at the Broad Institute of MIT and Harvard. The Sheng lab is a highly collegial and collaborative environment consisting of postdocs and graduate students who have the freedom to pursue a broad range of projects in the areas. Cambridge, MA 02142 (Kendall Square area) Explore . The four magnified images on the right show how the cell takes up the treatment across a span of 30 seconds. He is an associate member of the Broad Institute. Broad Institute 4.0. Published by at July 3, 2022. US 6342654 B1. University of Minnesota 4.2. his work to improve single-cell research protocols and technologies and how he transitioned from dentistry to life in a lab.Read more . Morgan Sheng Co-Director of the Stanley Center for Psychiatric Research at the Broad Institute; Professor of Neuroscience, Department of Brain and Cognitive Sciences, MIT Bipolar Disorder and Schizophrenia: from human genetics towards neurobiological mechanisms Susan Dymecki Professor of Genetics, Harvard Medical School Todd McDevitt, PhD Senior Investigator, Gladstone Institutes . In 2021, our sustainability efforts sent more than 80 percent of waste from the Genomics Platform to either a recycling facility or to an incineration plant that generates electricity. Her Juanchi is an electrophysiologist and cell biologist with a particular interest in the regulation of ion channels and how this understanding can be harnessed for potential disease interventions. All Rights Reserved. Apply Now Job Salary Company Rating Job Description The Broad Institute of MIT & Harvard is looking for outstanding postdoctoral scholars to join the laboratory of Morgan Sheng, Co-Director of the Stanley Center for Psychiatric Research Matt received a Ph.D. in Chemical Engineering from the University of Maryland in 2001. More than 11,000 individuals living with cancer in the United States and Canada have partnered with Count Me In to share their experiences and help accelerate cancer research. Mark Inman, MBA COO and Administrator . 617-714-7021. A cleaning revolution: How JCS-Echigo partnered A*STAR to clean faster and smarter. Access free classroom materials and more for STEM educators, parents, students, tutors, and others. Chang MC, Srinivasan K, Friedman BA, Suto E, Modrusan Z, Lee WP, Kaminker JS, Hansen DV, Sheng M. J Exp Med. Affiliated Research Lab Inner Ear Electrophysiology Laboratory; Academic profile. 10 The Xpert test has shown both accurate performance in . Virginia Tech Carilion Research Institute scientists have developed new imaging techniques to watch dangerous brain tumor cells respond to treatment in real time. The successful candidate will join a multidisciplinary group and perform cutting-edge basic and/or translational research on the molecular, cellular and .